Search results for " viral vectors"

Article Ensuring Viral Safety of Viral Vaccines and Vectors
Ensuring Viral Safety of Viral Vaccines and Vectors Viral vaccines and viral vectors used in biotherapeutic applications carry the risk of microbial contamination, which must be addressed. …

Article Scalable Viral Vector Manufacturing
In the last couple of years, there have been several new approved therapeutics based on viral vectors and many more are in the development pipeline. This results in a large demand for viral vector pro…

Article Achieve Scalable Viral Vector Production
In our tutorial series on viral vector production, GE scientists share their insights on virus production and how to tackle viral vector manufacturing challenges. In this episode, a scalable productio…

Article Manufacturing of Viral Vectors
In gene therapy, viral vectors can be used for the delivery of functional genes to replace defective genes to cure genetic disorders. As a vaccine platform, viral vectors can be used for the expressio…

Poster Process economy modeling for viral vector production
Viral vectors, such as adenovirus, adeno-associated virus, and herpes simplex virus, can be used in cancer therapeutics and in vaccines for chronic diseases and are thus expected to become high-valu…

Article A Look at the Affinity Chromatography Landscape
…purification of not only novel protein-based biologics, but a wide range of other biomolecules, from viral vectors and nucleic acids to cells. Beyond impurity removal for “simple” proteins Aff…

Article Bioterminology: A Guide to the Biopharmaceutical Lexicon
Bioterminology: A Guide to the Biopharmaceutical Lexicon This lexicon was generated by the editors of BioPharm International magazine. Please feel free to email your suggestions for terms that s…

Article Addressing the challenges in downstream processing today and tomorrow
…cines, antibody-drug conjugates, nonantibody protein scaffolds, PEGylated proteins and peptides, and viral vectors.  Some of the newer BioTx use nonmammalian expression systems such as yeast and …

Article Scaling Up Novel Therapies
“Many processes rely on the culture of adherent cells for producing a range of biological molecules, including viral vaccines, viral vectors for gene therapy, and oncolytic viruses. Producing these th…

Article Lessons Learned Accelerate Vaccine Development
Redlich agrees, “Having a deep understanding of vaccine manufacturing technology--preferably platform technologies, whether for adeno viral vectors or bacterial vectors, is crucial for achieving rapid…

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