Search results for " viral vectors"

Article Ensuring Viral Safety of Viral Vaccines and Vectors
Ensuring Viral Safety of Viral Vaccines and Vectors Viral vaccines and viral vectors used in biotherapeutic applications carry the risk of microbial contamination, which must be addressed. …

Article Scalable Viral Vector Manufacturing
In the last couple of years, there have been several new approved therapeutics based on viral vectors and many more are in the development pipeline. This results in a large demand for viral vector pro…

Article Manufacturing of Viral Vectors
In gene therapy, viral vectors can be used for the delivery of functional genes to replace defective genes to cure genetic disorders. As a vaccine platform, viral vectors can be used for the expressio…

Poster Process economy modeling for viral vector production
Viral vectors, such as adenovirus, adeno-associated virus, and herpes simplex virus, can be used in cancer therapeutics and in vaccines for chronic diseases and are thus expected to become high-valu…

Article Bioterminology: A Guide to the Biopharmaceutical Lexicon
Bioterminology: A Guide to the Biopharmaceutical Lexicon This lexicon was generated by the editors of BioPharm International magazine. Please feel free to email your suggestions for terms that s…

Article Addressing the challenges in downstream processing today and tomorrow
…cines, antibody-drug conjugates, nonantibody protein scaffolds, PEGylated proteins and peptides, and viral vectors.  Some of the newer BioTx use nonmammalian expression systems such as yeast and …

Article Scaling Up Novel Therapies
“Many processes rely on the culture of adherent cells for producing a range of biological molecules, including viral vaccines, viral vectors for gene therapy, and oncolytic viruses. Producing these th…

Article Lessons Learned Accelerate Vaccine Development
Redlich agrees, “Having a deep understanding of vaccine manufacturing technology--preferably platform technologies, whether for adeno viral vectors or bacterial vectors, is crucial for achieving rapid…

Article Developing an Efficient Adenovirus Downstream Purification Process
Adenovirus is one of the most frequently used viral vectors in the development of therapeutic vaccines and adenovirus is evaluated as vaccine delivery system in many preclinical and clinical studies…

Article Achieving Efficient Adenovirus Upstream Production
Adenovirus is one of the most frequently used viral vectors in the development of therapeutic vaccines and vaccines against infectious diseases. Adenovirus has also been explored as a viral vector f…

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