Search results for " high throughput process developmen…"

Article The Development and Application of a Monoclonal Antibody Purification Platform
A purification scheme to maximize the efficiency of the purification process and product purity while minimizing the development time for early-phase therapeutic antibodies. The following ar…

Article Development of Purification for Challenging Fc-Fusion Proteins
Development of Purification for Challenging Fc-Fusion Proteins This study outlines methods for an alternative protein-polishing process for challenging proteins. …

Article Developing a mAb aggregate removal step by high throughput process development
By Gustav Rodrigo and Kristina Nilsson-Välimaa ABSTRACT This article presents a case study illustrating the benefits of using a high throughput process development (HTPD) approach for choice o…

Article Process Development: What May Lie Ahead in 2018?
2018 is shaping up to be an interesting year in the world of biopharmaceuticals. What have 2017 developments taught us, and what may lie ahead for biopharmaceutical drug developers and process engin…

Article High-Throughput Process Development in an Historical Environment
Presentations, discussions, and information-sharing on modern bioprocess technology and high-throughput process development (HTPD) in an historical and culturally enriched environment is the essence…

Article High-throughput process development and scale-up of an intermediate purification step for recombinant insulin
This Application note describes high-throughput process development with PreDictor™ plates and Assist software to develop the intermediate purification step of insulin derived from E. coli. This rev…

Article Free Webinar: Smart Process Development of Chromatography Steps
Smarter development of chromatography processes reduces timelines and improves outcomes. Date: September 24, 2019 Smart process development is a collection of approaches to improve and spee…

Article Rapid process development for the purification of a MAb using ÄKTA™ avant 25
Abstract ÄKTA avant 25 system controlled by UNICORN™ 6 software was used to develop a two-step chromatography process for purification of a monoclonal antibody (MAb). MabSelect SuRe™, a pro…

Poster Rapid Process Development of a CIEX Step for a Biosimilar
A standardized workflow was adapted using a high throughput process development (HTPD) approach: chromatography resin and running conditions were selected based on experience and adapted to meet requi…

Poster Experimental investigation of scale effects in high throughput process development studies
High throughput process development (HTPD) has already been proven successful, mainly because it allows for faster investigation of larger experimental space of process conditions, with smaller sample…

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