Search results for " SPR"

Article Get Acquainted with How SPR Technology is Used for Better Protein Characterization
Stay up-to-date with our new e-book on the latest in SPR technology and use in the fields of process development and product quality control. Download the free e-book on Better Biotherapeutic Char…

Article Videos! SPR Applications in Protein Characterization
In these exclusive videos from the Biacore Analytical, Comparability and QC Symposium, Vienna, November 2017, industry thought-leaders share insights, tips, and techniques that illuminate how SPR with…

Poster Improving influenza vaccine quantification; a comparative study of SRID and SPR
Results showed the SPR-based assay to have higher sensitivity (detection range 0.5 μg/ml to 10 μg/ml), higher precision and significantly shorter analysis and hands on time compared with SRID.

Poster Towards an optimized in-vitro SPR assay for antibody
Therapeutic antibodies are now approved for a number of different indications. One important antibody (Ab) attribute is its Fc effector function, and Abs are now being engineered with the aim of obt…

Article Applications of Surface Plasmon Resonance for Detection of Bispecific Antibody Activity
ELISA and SPR are commonly used for in-vitro confirmation of biological activity by measuring interactions with antigens, receptor, Fc-receptors, or other binding proteins (11, 13). Cell- or animal-ba…

Article Ligand-Binding Assays and the Determination of Biosimilarity
Advances in SPR analysis have resulted in increased robustness of the assays and reduced operator influence, as well as increased throughput for the determination of binding affinities. Biolayer inter…

Article Sensitive and Reproducible SPR-Based Concentration and Ligand-Binding Analyses
Surface plasmon resonance (SPR) assays are used across the life cycle of a biopharmaceutical, from target identification, through CQA determination, development, and on-going quality control. This art…

Article Impurity Testing of Biologic Drug Products
Experts share insights on the various methods used for purity and impurity analysis of therapeutic proteins. By Adeline Siew, PhD  CA-SSIS/shutterstock.comIm…

Poster High-Resolution SPR-Based Surrogate Potency Assay to Facilitate Comparability and Biosimilar Studies
An array of potency assays is needed to measure and monitor critical quality attributes (CQA) of antibody therapeutics. The poster shows how Biacore™ surface plasmon resonance (SPR)-based assays can b…

Poster Performance of a fast Surface Plasmon Resonance based MAb quantification method
Monoclonal antibodies (MAb) are large complex molecules with many possible modifications that may affect safety and efficacy. Hence, many different analytical methods and techniques are needed to ch…

Next Page