Search results for " SPR"

Article Get Acquainted with How SPR Technology is Used for Better Protein Characterization
Stay up-to-date with our new e-book on the latest in SPR technology and use in the fields of process development and product quality control. Download the free e-book on Better Biotherapeutic Char…

Article Videos! SPR Applications in Protein Characterization
In these exclusive videos from the Biacore Analytical, Comparability and QC Symposium, Vienna, November 2017, industry thought-leaders share insights, tips, and techniques that illuminate how SPR with…

Poster Improving influenza vaccine quantification; a comparative study of SRID and SPR
Results showed the SPR-based assay to have higher sensitivity (detection range 0.5 μg/ml to 10 μg/ml), higher precision and significantly shorter analysis and hands on time compared with SRID.

Poster Towards an optimized in-vitro SPR assay for antibody
Therapeutic antibodies are now approved for a number of different indications. One important antibody (Ab) attribute is its Fc effector function, and Abs are now being engineered with the aim of obt…

Article Real-Time Characterization of Biotherapeutics and Comparability of Biosimilars
In SPR, one of the interactants is immobilized to the sensor surface and the other is kept free in solution and passed over the surface. Association and dissociation are measured and displayed in the …

Article Applications of Surface Plasmon Resonance for Detection of Bispecific Antibody Activity
ELISA and SPR are commonly used for in-vitro confirmation of biological activity by measuring interactions with antigens, receptor, Fc-receptors, or other binding proteins (11, 13). Cell- or animal-ba…

Article Ligand-Binding Assays and the Determination of Biosimilarity
Advances in SPR analysis have resulted in increased robustness of the assays and reduced operator influence, as well as increased throughput for the determination of binding affinities. Biolayer inter…

Article Sensitive and Reproducible SPR-Based Concentration and Ligand-Binding Analyses
Surface plasmon resonance (SPR) assays are used across the life cycle of a biopharmaceutical, from target identification, through CQA determination, development, and on-going quality control. This art…

Article Make the Switch from ELISA to Biacore™ SPR-Based Assays Today
General guidance on how to convert an existing ELISA assay to a Biacore surface plasmon resonance (SPR) assay and how, by doing so, you can get results in less than half the time compared with ELISA. …

Article Sensitive and Reproducible SPR-Based Concentration and Ligand-Binding Analyses
Surface plasmon resonance (SPR) assays are used across the life cycle of a biopharmaceutical, from target identification, through CQA determination, development, and on-going quality control. This art…

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