Search results for " SPR"
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Ligand-Binding Assays and the Determination of Biosimilarity
Advances in SPR analysis have resulted in increased robustness of the assays and reduced operator influence, as well as increased throughput for the determination of binding affinities. Biolayer inter…
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Virus-like Particles as Therapeutic Moieties of the Future
…erformance liquid chromatography, IVRP assay, MS, native agarose gel electrophoresis, RP–HPLC, and SPR (1,6,15,20,24,27–32).
These biophysical, biochemical, and immunochemical methods ensure proc…
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Reimagining Affordable Biosimilars
With new configurations and solid-state designs, SPR has become a workhorse in protein and nucleic acid applications. The sensor surfaces have been modified to allow cell-based binding to mimic real-t…
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Getting it Right from the Start in the Drug Development Process
Click here to read more on how the use of surface plasmon resonance (SPR) technology may add value in drug development and how SPR assays are validated and implemented in regulated workflows.
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Join DiPIA 2022
Don’t miss out on latest applications and developments in biophysical characterization, join our two half-days conference where researchers will present their work using surface plasmon r…
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Finding the Needle in a High-Dimensional, Information-Rich Data Haystack Can Be Time Consuming
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Biacore™ surface plasmon resonance (SPR)-based sensors are an essential tool in drug discovery. With these tools, scientists can detect and characterize low molecular …
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Epitope Binning: A Critical Step in Antibody Selection
Read about how surface plasmon resonance (SPR) is used to characterize closely related “bins” of monoclonal antibodies (mAbs) targeting the same epitope of the target protein, and how the selection …
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Webinar On-Demand: Novel Analytics to Improve Bioprocessing and Validation Guideline
At the recent Biotherapeutics Analytical Summit, Fredrik Sundberg presented the importance of implementation of a robust analytical control strategy to ensure drug product efficacy and patient safet…
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Are You in Control of the Quality of Your mAbs?
Better biotherapeutic characterization for improved quality control
At the recent WCBP conference in Washington, D.C., Dr. Stuart Knowling from Antibody Analytics presented how the latest innovati…
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Sensitive and Reproducible SPR-Based Concentration and Ligand-Binding Analyses
Surface plasmon resonance (SPR) assays are used across the life cycle of a biopharmaceutical, from target identification, through CQA determination, development, and on-going quality control. This art…