Search results for " buffers"

Article Virus purification using superheated buffer in place (SBIP) for packed bed chromatography
Superheated buffer in place (SBIP) is a method for sterilizing packed chromatography beds used to process viruses and biomolecules that are too large for sterile filtration. Superheating occurs when…

Article Will My Buffers Work When Using an Inline Conditioning System?
In-line preparation of buffers from highly concentrated, single-component stock solutions saves both time and storage space. Compared with preparing one concentrate per buffer formulation, many differ…

Article Make buffer preparation more time and cost efficient with inline conditioning
Preparation of these buffers is a challenge that in-line conditioning can overcome. Inline conditioning simplifies buffer preparation and offers significant reduction in number of tanks, buffer soluti…

Article Automated In-Line Buffer Preparation from Ready-Made Stock Solutions in a mAb Process Step
To further reduce the time and space required, ready-made stock solutions delivered in disposable bags were connected directly to the Inline Conditioning system and feedback regulation of the final bu…

Article Overcoming Buffer Challenges With In-Line Conditioning
With IC, buffers of desired formulations are prepared from smallvolume single-component stock solutions at the time of need. Formulating buffers from single-component stock solutions eliminates the ne…

Poster Buffer plate preparation using ÄKTA™ avant system and BufferPro tool
Manual buffer preparation for high-throughput process development (HTPD) requires a lot of effort as the number of different buffer conditions is large. A method was developed for automatic buffer p…

Poster Overcoming buffer challenges in plasma production with in-line conditioning
Buffer preparation in the plasma industry is a challenge. One industry trend is in-line dilution to reduce the floor space needed for buffer preparation and storage as well as to enable the use of b…

Poster In-line buffer conditioning for biopharmaceutical manufacturing
There is a need to decrease costs in labor and space, this need can be met by formulating the buffers in-line using concentrated stock solutions and water for injection (WFI). In-line Conditioning (IC…

Article Immediate, Flexible Capacity with Hydrated Buffers and Process Liquids
Historically, bioprocessing facilities have prepared buffers and process liquids in-house as a core activity. However, trends suggested buffer fluid preparation is one area seeing increase activity in…

Poster Scaling In-Line Buffer Preparation from Process Development to Manufacturing
Preparing buffers for large-scale chromatography requires significant resources: time, money, and storage space. Inline conditioning (IC) is one possible way to address these challenges. At the same t…

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