Search results for " ion exchange"

Article Updated Ion Exchange Chromatography (IEX) Handbook
In addition to a new chapter on large-scale purification, the handbook describes each product and how to use them, and provides useful hints and tips for getting great results from your ion exchange c…

Article New Selection Guide: Ion Exchange Chromatography Columns and Resins
Use these decision trees to find the most appropriate resin for your needs. Download

Article Reduce Hands-On Time in Your Ion Exchange Chromatography Runs
Optimization and improvements in ion exchange chromatography can be time consuming. Luckily, there are several tools that greatly facilitate this. Explore four valuable tips for reducing IEX hands-on …

Article Online Ion Exchange Chromatography (IEX) Resource Hub—All in One Place
If you use ion exchange chromatography, check out GE Healthcare's online IEX resource hub for useful information, from fundamentals to tips for advanced practitioners. Read more

Tip How to screen for binding conditions with high-capacity ion exchangers
Some proteins exhibit unexpected behavior on ion exchangers that have been engineered for extra high binding capacity. For example, dynamic binding capacity for a specific molecule might increase wh…

Poster Polishing of monoclonal antibodies using a polymer grafted cation exchanger
A typical monoclonal antibody (MAb) purification process begins with capture on a protein A chromatography medium (resin), followed by polishing steps by for example ion exchange chromatography. The …

Resource Tips for successful ion exchange chromatography
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Article Bioterminology: A Guide to the Biopharmaceutical Lexicon
Bioterminology: A Guide to the Biopharmaceutical Lexicon This lexicon was generated by the editors of BioPharm International magazine. Please feel free to email your suggestions for terms that s…

Article Purification Strategies to Process 5 g/L Titers of Monoclonal Antibodies
This requires the modification of a platform purification process comprising Protein A chromatography as the robust capture step followed by two ion exchange chromatography steps. Because buffer and p…

Article Evolution of the Monoclonal Antibody Purification Platform
Though extremely efficient and effective, the step primarily suffers from the significantly high cost of Protein A resins in comparison to other popular modes of chromatography (such as ion exchange).…

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