Search results for "column packing" in Articles / App Notes
Article
Selection Guide Size Exclusion Chromatography Columns and Media
Size exclusion chromatography (SEC), also called Gel filtration (GF), separates molecules on the basis of differences in size as they pass through a SEC medium packed in a column. A variety of media…
Article
Sanitization of AxiChrom™ Columns Packed with Chromatography Resin
This study evaluates sanitization methods based on 1 M sodium hydroxide (NaOH) as sanitization agent using methodology previously developed for peracetic acid (PAA).
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Article
Your Reliable Downstream Bioprocessing. Our Proven AxiChrom Columns
Traditionally, column packing has been considered a bottleneck. By eliminating this concern, you can focus on the core process.
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Article
Optimizing Resin Performance with Disposable Chromatography Solutions
Although the initial uptake of single-use chromatography solutions has been relatively slow, an increased need for higher-capacity resins and the demand for smaller batches has made disposable chrom…
Article
Process Chromatography Selection for Downstream Processing Applications
BioPharm: What are some common chromatography column issues one might experience? How can these issues be addressed?
Björkman (Cytiva): Some common chromatography column issues include:
• Colu…
Article
SEC in the Modern Downstream Purification Process
…n solution and the stationary phase, separations performed using SEC are sensitive to variations in column packing. A properly packed column is vitally important when using SEC, as the number of theo…
Article
Re-use of Protein A Resin: Fouling and Economics
Mar 01, 2015
By Anurag S. Rathore, Mili Pathak, Guijun Ma, Daniel G. Bracewell
BioPharm International
Volume 3, Issue 28
In the past two decades, Protein A affinity chromatography ha…
Article
Mechanistic Modeling of Preparative Ion-Exchange Chromatography
By Anurag Rathore, Vijesh Kumar
Among the various downstream processing unit operations that are used for purification of biotech products, chromatography is uniquely capable of providing resolu…
Article
Development of Purification for Challenging Fc-Fusion Proteins
Development of Purification for Challenging Fc-Fusion Proteins
This study outlines methods for an alternative protein-polishing process for challenging proteins.
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Article
Single-Use for Downstream Chromatography: Benefit or Hindrance?
Among the common problems that single-use technology can help address is column packing. Column packing requires a stable bed with good flow properties, and, today, automatic packing solutions make pa…