Search results for "buffer management"

Article Buffer Management Solutions for Large-Scale Biomanufacturing
Learn how different approaches can resolve buffer management challenges in large-scale biomanufacturing. This article discusses solutions such as inline conditioning, outsourcing buffer preparation,…

Article Automated In-Line Buffer Preparation from Ready-Made Stock Solutions in a mAb Process Step
Buffer preparation is both time-and space-consuming and can easily become a challenge in biomanufacturing. This application note describes a lean approach to buffer preparation by implementing in-li…

Article Overcoming Buffer Challenges With In-Line Conditioning
Preparation and storage of the large number of buffers required for biopharmaceutical production can be a challenge, particularly in large production scale. In this application note, we show how in-…

Article Automated Buffer Preparation – Increasing Production Capacity While Maintaining Footprint
Buffer preparation requires extensive footprint and is also resource intensive. In fact, buffer preparation is known to be one of the most resource-intensive activities in biomanufacturing, as large…

Article Can You Trust a Machine for Downstream Bioprocess Buffer Preparation?
Some of the questions to be answered are:    - Can automated buffer management solutions save resources and maintain the quality?   - Is automated buffer preparation a solution to the dilemma …

Article Efficient and Scalable Buffer Preparation
This article describes how to ensure a scalable process for buffer management from process development to manufacturing with inline conditioning (IC). It also explains how ÄKTA avant can be used …

Article Monitoring and Control of Inline Dilution Processes
Buffer management has received less attention, despite the high costs and labor-, space-, time-, and material-intensive nature of this common downstream activity. Inline dilution (ILD) combined with i…

Article Bioterminology: A Guide to the Biopharmaceutical Lexicon
Bioterminology: A Guide to the Biopharmaceutical Lexicon This lexicon was generated by the editors of BioPharm International magazine. Please feel free to email your suggestions for terms that s…

Article Process Chromatography Selection for Downstream Processing Applications
Industry experts discuss best practices for selecting a separation technology. By Caroline Hroncich Process chromatography has changed significantly since it was first introduced to the biop…

Article Ready-to-use fluid management for inline conditioning (IC) large-scale chromatography systems
There is an increasing interest in IC systems because they; (i) are relatively customizable; (ii) reduce the need for large storage tanks, and (iii) are economical. These features combine well with …

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