Search results for "SPR"
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Ligand-Binding Assays and the Determination of Biosimilarity
SPR measures binding in terms of the “change in mass” that occurs as the ligand and binding partner attach to one another and then separate. Advances in SPR analysis have resulted in increased robustn…
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Virus-like Particles as Therapeutic Moieties of the Future
Various analytical tools can be used to analyze the size of VLPs, such as electrospray-differential mobility analysis (ES–DMA), asymmetrical flow field-flow fractionation with multiple angle light sca…
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Reimagining Affordable Biosimilars
The field has seen simultaneous advances on multiple forefronts of instrumentation, including ionizers, such as matrix-assisted laser desorption/ionization, electrospray ionization (ESI), and nano-ESI…
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Getting it Right from the Start in the Drug Development Process
Click here to read more on how the use of surface plasmon resonance (SPR) technology may add value in drug development and how SPR assays are validated and implemented in regulated workflows.
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Join DiPIA 2022
Don’t miss out on latest applications and developments in biophysical characterization, join our two half-days conference where researchers will present their work using surface plasmon r…
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Finding the Needle in a High-Dimensional, Information-Rich Data Haystack Can Be Time Consuming
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Biacore™ surface plasmon resonance (SPR)-based sensors are an essential tool in drug discovery. With these tools, scientists can detect and characterize low molecular …
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Epitope Binning: A Critical Step in Antibody Selection
Read about how surface plasmon resonance (SPR) is used to characterize closely related “bins” of monoclonal antibodies (mAbs) targeting the same epitope of the target protein, and how the selection …
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Webinar On-Demand: Novel Analytics to Improve Bioprocessing and Validation Guideline
He also covered the latest regulatory strategies and a new assay validation guideline for surface plasmon resonance (SPR) technology.
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Are You in Control of the Quality of Your mAbs?
Stuart Knowling from Antibody Analytics presented how the latest innovation in surface plasmon resonance (SPR) technology has been adopted to develop and qualify assays for monoclonal antibodies (mAbs…
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Sensitive and Reproducible SPR-Based Concentration and Ligand-Binding Analyses
Surface plasmon resonance (SPR) assays are used across the life cycle of a biopharmaceutical, from target identification, through CQA determination, development, and on-going quality control. This art…