Search results for " cell therapy"
Article
Patenting Prospects for Cell-Based Therapies
For example, the NurOwn cell therapy product (Brainstorm Cell Therapeutics, Inc.) is comprised of autologous mesenchymal stem cells (MSCs) modified to express neurotrophic factors, shown to promote mo…
Article
Downstream Processing for Cell-Based Therapies
By Qasim A. Rafiq, Fernanda Masri
With increasing numbers of advanced therapies—including cell and gene therapies—entering early- and late-stage clinical development, significant focus has been …
Article
Gene Therapies Push Viral Vector Production
Gene Therapies Push Viral Vector Production
Viral vectors show promise as a delivery mechanism for gene therapy, but which virus types are commercially viable?
By Feliza Miraso…
Article
Science Focus Fuels Successful Process Development for Startups
…y developing cell therapies for immuno-oncology and autoimmune indications using its proprietary SQZ cell therapy platform, also known as cell squeezing. “There are no established protocols for how t…
Article
Single-Use Technologies Prove Effective for Viral Vector Process Development
Finally, Tan notes that there is a general consensus among end users that the next innovation in gene therapy and gene-modified cell therapy will be achieving stable producer cell lines for viral vect…
Article
FDA Framework Spurs Advanced Therapies
Greater clarity on the application of existing regulations will accelerate development of cell and gene therapies.
By Cynthia A. Challener
Ibreakstock/Shutterstock.co…
Article
Emerging Therapies Test Existing Bioanalytical Methods
The technology allows for real-time monitoring of the cell therapy in vivo and can support the qPCR data for PK. Flow panels can be designed to evaluate the expression and persistence of the construct…
Article
Bracing for a Future Wave of Advanced Therapies
Among these are the first ever approval of an adoptive cell therapy for solid tumors in the US, and the first US approval of an allogeneic T-cell therapy. The industry can also potentially see additio…
Article
Improving Upstream Predictability
Better understanding and control of cell behavior is yielding benefits, upstream and beyond.
By Agnes Shanley
In the earliest days of biotech, developers often struggled to sust…
Article
Manufacturing Standards Key to Advancing Cellular and Gene Therapies
Bryan Silvey, senior director for quality compliance at Kite Pharma, emphasized that personalized cell therapy production, utilizing a “one lot-one patient” manufacturing platform with a 15-d…