Search results for " titer" in Articles / App Notes

Article Webcast: Repeatable, automated SPR titer assay for adeno- and adeno-associated viruses in crude samples
Fredrik Sundberg at Cytiva shares our recent SPR assay developments for measuring adenovirus and adeno-associated virus titers. WATCH NOW >> 

Article Cell Culture Media Considerations and Optimization for Improved Titers and Protein Quality
…es View our Cell Culture Media and Feeds Read our case study on Improving Cell Culture Titer and Protein Quality

Article Comparing Protein A Resins for Monoclonal Antibody Purification
With greater economic pressure on monoclonal antibody (mAb) production for therapeutic and research uses, antibody titers in mammalian cell culture have increased dramatically over the past 20 years. …

Article Generating a Fully Processed Antibody
…rotein needs to be produced at high enough levels to fully process all the biopharmaceutical at high titers without interfering with normal cell growth and the secretion of the molecule. Finally, som…

Article The Development and Application of a Monoclonal Antibody Purification Platform
…division, including how the individual unit operations have been affected by increasing cell culture titers and subsequent changes in the impurity profile, as well as viral clearance issues. The plat…

Article Gene Therapies Push Viral Vector Production
This makes it relatively straightforward to achieve desired titers and to achieve a single integration element, Carstens emphasizes. Downsides include the fact that it is more difficult to achieve lar…

Article Concentrating Feed—an Applicable Approach to Improve Antibody Production
Cell counts, antibody titer, protein quality analysis, and qPCR array. Cell-culture samples were counted by a Vi-CELL (Beckman-Coulter) using the trypan blue exclusion method. The pH and metabolites i…

Article Technology Innovations Improve Process Chromatography Performance
Perfusion titers will increase over time like batch processes have previously. This will create a need for downstream process improvements that are being developed today,” Scanlon adds. Continuous…

Article Challenges in Cell Harvesting Prompt Enhancements
The past decade has seen the biopharmaceutical industry move toward significantly higher titers, and, as a result, higher cell densities. Biomanufacturers have been shifting from large stainless-steel…

Article Top Process Development Trends for 2021 and a Look into 2022
Implementing Titers, Compliance, Mechanistic Modeling of Chromatography for Smarter Process Development Bioprocessing has evolved over the past 30 years, and readers how curious how to navigate the…

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