Search results for " screening"

Article High-throughput screening methods to speed MAb process development
Combining such savings with rapid screening and optimization means further gains at the start of purification development. Add highly robust scale-up and the stage is set for shortening the time-to-cl…

Article Resolving a bottleneck in screening and characterization of recombinant antibody fragments using Biacore 4000
This method provides rapid screening in combination with data-rich selection of fragments with high affinity and the desired kinetic behavior. Kinetic analysis at different temperatures provided addit…

Article High-throughput screening and process development for capture of recombinant pro-insulin from E. coli
High-throughput screening quickly narrowed down the number of candidate chromatography media and suggested binding and elution conditions for further investigation. When capture step conditions were f…

Article High-throughput screening of HIC media in PreDictor™ plates for capturing recombinant Green Fluorescent Protein from E. coli
This study demonstrates a rapid, high-throughput process development workflow using parallel screening in 96-well plates to determine the most suitable HIC media and conditions for capturing recombina…

Article Single-Step, Protein A Chromatography Process for Bispecific Antibodies in Early Screening
BsAb constructs were efficiently purified to give more than 90% purity and 85% yield in the early screening downstream process. Learn more about bispecific purification

Poster Single-Step, Protein A Chromatography Process for Bispecific Antibodies in Early Screening
BsAb constructs were efficiently purified to give more than 90% purity and 85% yield in the early screening downstream process.

Article Walk Away and Do More Screening Preps
Developing a process or looking for a clone of interest often requires screening large numbers of samples. Many analyses require purified protein, and substantial hands-on time might be allocated to…

Poster Utilization of high-throughput screening in the development of HyCell™ CHO medium
In order to overcome these limitations, this poster investigates the use of various high throughput screening (HTS) equipment in the development and testing of a medium designed for multiple CHO clone…

Article High-throughput screening and optimization of a multimodal polishing step in a monoclonal antibody purification process
The complexity of multimodal media requires a more thorough process optimization study in order to take full advantage of the outstanding potential of this technology. This calls for the development…

Tip Streamlining Screening: Hydrophobic interaction chromatography (HIC)
Perhaps you are one of those who have stayed clear of HIC because of the large range of products that need to be screened and the even larger range of conditions that need to be tested to optimize a…

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