Search results for " upstream" in Articles / App Notes

Article QbD and PAT in Upstream and Downstream Processing
UPSTREAM PROCESSING BioPharm: In implementing QbD, what would you identify as the critical quality attributes (CQAs) in a typical upstream bioprocess using cell-culture? Vanden Boom (Hospi…

Article Maximum Output Starts with Optimized Upstream Processing
Challener Biopharmaceutical companies and contract manufacturers respond to changing demand dynamics for upstream bioprocessing capacity. Significant growth in the development and manufa…

Article Improving Upstream Predictability
Today, better understanding of cells and how they interact with their environment has enabled improvements in most aspects of upstream processing, from bioreactor design and media development to proce…

Article Analytical Considerations for Successful Upstream Process Development with Spivey and Lane
…: Welcome to the BioPharm International expert interview on analytical considerations for successful upstream process development. This interview, conducted independently by the editors of BioPharm I…

Article Remote Monitoring and Big Data Advance Upstream Automation
Challener As upstream processing drives toward higher efficiencies in meeting demand, it requires optimizing the current state of manufacturing with the goal of achieving real-time release and an …

Article Automating Processes in Upstream Processing
BioPharm: What specific challenges do companies face when automating upstream processes? Marshall: New product introductions into existing facilities often require new equipment process capabiliti…

Article Maximizing the Effectiveness of Upstream Bioprocessing Through the Combination of Lab Informatics and Instrumentation
By Claire Hill The biopharmaceutical market continues to expand at a rapid pace and the demand for upstream manufacturing capacity, particularly for growth areas such as viral vectors, is growing …

Article What’s New in Upstream Technologies
The system features a modular, scalable, fixed-bed bioreactor for enhanced upstream processing of viral products, including viral vaccines, viral vectors, and oncolytic viruses. The low-footprint inte…

Article Upstream PD Time-Saver: Optimize Early
Identify the right combination of culture medium, feed supplements, and feeding strategy early in upstream process development to conserve precious time and resources.

Article Recent Trends in Data Analytics for Upstream Process Workflows
Modeling techniques can improve process control and monitoring in biopharmaceutical production. Read more about it here >>

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