Search results for " microcarrier"

Poster Validation of the Production of Influenza Virus
To reduce the need for microcarrier preparation prior to use, presterilized and ready-to-use Cytodex Gamma microcarriers were evaluated and compared with Cytodex microcarriers. The results show compar…

Article Validation of the production of influenza virus in ReadyToProcess WAVE™ 25 bioreactor system
To reduce the need for microcarrier preparation prior to use, presterilized and ready-to-use Cytodex Gamma microcarriers was evaluated and compared with Cytodex microcarriers. The results show compara…

Article Downstream Scale-up Purification of Influenza Virus Using ReadyToProcess Equipment
The cells were grown on Cytodex™ 1 microcarriers (GE Healthcare Life Sciences) with a concentration of 3 g/L and in Dulbecco’s modified eagle medium (DMEM)/Ham’s F12 (GE Healthcare Life Sciences) supp…

Article Scalable ADCF Virus Production Using HyClone™ VaccineXpress Medium
Small-scale microcarrier cultures were optimized using spinner flasks by closely monitoring cell growth, viability, and morphology. The results were used for scaling up the process to a ReadyToProcess…

Poster Validation of Cytodex™ Gamma microcarrier-based virus production in single-use bioreactor systems
Here, we describe different approaches for the cultivation of Vero cells using Cytodex and Cytodex Gamma microcarriers in serum-free cultivation medium using spinners, WAVE Bioreactor™ 20/50, ReadyToP…

Poster Optimization of microcarrier-based virus production in single-use rocking bioreactor systems
In this work, a comparison of Vero cell expansion using the microcarriers Cytodex™ 1 and presterilized Cytodex 1 Gamma* in serum-free cell culture medium is described.

Article Bioterminology: A Guide to the Biopharmaceutical Lexicon
In large-scale vaccine production, roller bottles have been replaced by microcarrier culture systems that offer the advantage of scale-up, minimizing contamination.  R subgroup (or side chain) The…

Article Flexible Facilities for Viral Vector Manufacturing
Another option would be to use adherent cells with microcarriers in stirred-tank bioreactors. Both options typically do not have scale limitations and thus would allow for a more scalable process. …

Article Mapping a Route for Cell and Gene Therapy Process Development
While cell and gene therapies differ in many ways, some of the best practices for process development and validation are similar. By Cynthia A. Challener …

Article Scaling Up Novel Therapies
Scaling Up Novel Therapies Platform processes have improved monoclonal antibody scale-up. Can they do the same for personalized therapies? By Agnes Shan…

Previous PageNext Page