Search results for "cell therapy"
Article
Adherent Cell Culture in Biopharmaceutical Applications: The Cell-Detachment Challenge
The necessity to detach cells from a culture substrate during cell harvesting remains one of the most challenging steps in a cell-culture process.
By Marcos Simon, Juan J. Giner-Casares
Cell…
Article
The Evolving Role of Starting Materials in Cell and Gene Therapy
Cell therapy starting material—where does it feed into critical process points?
Donor recruitment: Necessary at each stage of clinical testing. Must have a strong donor netw…
Article
Mapping a Route for Cell and Gene Therapy Process Development
cell therapy applications), the focus of scaling of the manufacturing process may be different.
Scale up and mass production of the final product starting from a small seed bank (for instance, …
Article
Design Considerations for a Commercial Cell and Gene Therapy Facility
The workflows of a cell therapy or a gene therapy differ from each other and from those of therapeutic antibodies, so the design and layout of the manufacturing facility must take these workflows into…
Article
Changing the Culture of Cell Culture: Applying Best Practices and Authentication to Ensure Scientific Reproducibility
By Leonard P. Freedman, Mark C. Gibson, Richard M. Neve
Irreproducible preclinical research is a global, expensive, and well-recognized problem that contributes to delays and increased costs of …
Article
Best Practices for Selecting a Top-Quality Cell Line
Irina Shi - Stock.Adobe.com
Leveraging automation and a step-by-step approach are keys to success.
By Cynthia A. Challener
Cell lines determine the performanc…
Article
Taking a “Development-by-Design” Approach to Cell Therapies
More CDMOs are entering cell therapy market niche
Demand for specialized cell therapy manufacturing and development services is also growing, and has attracted Lonza Bioservices, Cognate BioService…
Article
FDA Seeks to Enhance Manufacturing of Cell and Gene Therapies
While there is great excitement over the potential of CAR-T (chimeric antigen receptor) cell therapy to target and activate T cells to eliminate a cancerous or other undesirable cell type, Marks cauti…
Article
Cytiva and 4Tune Engineering Collaborate on Cell Therapy Quality Risk Management
…t they have entered into an agreement to include 4Tune Engineering’s iRISK platform in Cytiva’s cell therapy product offering.
Cytiva customers in the early stages of cell therapy product developm…
Resource
Taking Digital Control of Cell Therapy Logistics: An Advanced Therapy Treatment Centre Network Case Study
Taking Digital Control of Cell Therapy Logistics: An Advanced Therapy Treatment Centre Network Case Study (May 27)