Search results for " Lentiviral vector"

Article Lentiviral Vector Upstream Process in Single-use Bioreactors
However, cost-effective manufacturing of lentiviral vectors at commercial scales has proven difficult and remains a pressing issue for the marketing of therapies that depend on their application. …

Article Improving Lentiviral Vector Downstream Processing Workflows
Lentiviral vectors (LVV) are a common vehicle to deliver genetic material in chimeric antigen receptor (CAR) T-cell therapy and gene therapy applications. Production methods have been developed by a…

Article Gene Therapies Push Viral Vector Production
For instance, Agilent has retroviral and lentiviral vector systems that are pseudotyped to achieve a wide target range. The upside of pseudotyping is a tailored target range. The downside is that some…

Article A Look at the Affinity Chromatography Landscape
The greatest demand is for lentiviral and adeno-associated viral (AAV) vectors, with sourcing of lentiviral vectors becoming a bottleneck for gene and cell therapy manufacturing. Traditionally, …

Article Getting Ahead of the Game in Cell and Gene Therapy
Here, we present an article based on an interview with Carol Knevelman, Vice President, Head of Process R&D at Oxford Biomedica, who shared a case study on large-scale lentiviral vector production at …

Article FDA Seeks to Enhance Manufacturing of Cell and Gene Therapies
FDA Seeks to Enhance Manufacturing of Cell and Gene Therapies More consistent and reliable production processes are critical for advancing innovative treatments. By Jill Wechsler …