Search results for "filtration"
Article
Register to the Chromatography + Filtration Virtual Summit 2024
Agenda
Day 1:
- Chromatography for antibodies and antibody variants
Day 2:
- Chromatography for recombinant proteins
- Filtration for antibodies and other recombinant proteins
Da…
Article
Filtration methods to overcome new challenges in viral safety
41 and ICH Q5A, and outlines the detailed mechanisms governing effective virus filtration, demonstrating how both specific methods and advanced filter design can overcome these challenges.
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Article
Detailed agenda for Chromatography + filtration virtual summit
Join Cytiva Chromatography and filtration summit online to learn from presentations, live Q&A, and panel discussions on recent advances in antibody, antibody variants, recombinant proteins, and gene t…
Article
Exosome isolation by tangential flow filtration and size exclusion chromatography
The workflows we describe are suitable for scale-up and combine tangential flow filtration (TFF) for the concentration of exosomes followed by gentle size exclusion chromatography (SEC) with our next-…
Webcast
Chromatography + Filtration Virtual Summit On Demand
Join Cytiva Chromatography and filtration summit online to learn how you can make your process development and scale-up smarter and faster!
Learn from presentations, live Q&A, and panel discussio…
Article
A risk based approach to sterile filtration
Drug quality cannot be assured only by finished-product testing. Process validation is required to establish scientific evidence that a process is capable of delivering an effective and safe …
Article
Challenges in Cell Harvesting Prompt Enhancements
Cell harvesting involves the separation of the cell-culture from the medium and running it through several techniques: centrifugation, microfiltration, depth filtration, and filtration through absolut…
Article
Downstream Processing for Cell-Based Therapies
Typically, a swing-bucket rotor centrifugation step or a filtration step is included to remove cell debris, large aggregates, unwanted proteins, volume reduce (i.e., concentrate), and formulate the ce…
Article
Updating Viral Clearance for New Biologic Modalities
Because viruses are typically smaller than downstream impurities such as host cell proteins (HCPs) and other extracellular debris, they require meticulous filtration, even in more established processe…
Article
Downstream Processing Continues to Worry CMOs
(Figure courtesy of author)
Chromatography and ultrafiltration
When it comes to specific steps that contribute to downstream-related capacity constraints, chromatography columns continue to be…