How to elute proteins from multimodal ch… January 14, 2013 - Tech Support Mixed mode ion exchangers frequently exhibit useful selectivity that can be exploited to achieve purification in fewer steps. Frequently, …

How to clean chromatography media and eq… January 7, 2013 - Tech Support Cleaning chromatography media and equipment is a complex subject and requires careful definition of what is meant by clean, as well as a t…

Formats for HTPD chromatography August 12, 2012 - Tech Support We all agree that high-throughput formats are very smart for screening many alternatives. Especially in the QbD era, where lots of experim…

An oldie but goldie March 5, 2012 - Tech support Well-packed chromatography columns can be run in either downward or upward direction and this offers a number of creative opportunities. T…

Smart purification strategies February 23, 2012 - Tech Support Perform stability tests as early as possible when designing a new purification scheme to avoid wasting valuable time testing a step that r…

MAb purification platforms February 6, 2012 - Tech Support Design the elution conditions from the Protein A resin to match the pH required for virus inactivation and avoid a subsequent adjustment o…

Differential scanning calorimetry (DSC) … January 30, 2012 - Tech Support Differential scanning calorimetry (DSC) has been found to be useful to help identify formulations that impact protein structure. Applicati…

Avoiding HIC-ups January 17, 2012 - Tech Support Although HIC (hydrophobic interaction chromatography) is a powerful purification technique, success can be a little hard to predict. Thing…

Do your regular housekeeping! January 3, 2012 - Tech Support Be smart and shut down your UNICORN™ controlled systems whenever they are not used for some period or if you change components or config…

Western blotting principles and methods December 27, 2011 - Tech Support Western blotting, or immunoblotting, was first described in 1979 and has since become one of the most commonly used methods in life-scienc…

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