December 15, 2023

A deep dive into optimizing AAV capture and polishing to maximize both yield and purity

As demand for AAV vectors grows, so does the need for scalable and cost-efficient purification processes. It’s critical to maximize both overall yield and removal of impurities, including empty capsids.

To meet these needs, Cytiva developed scalable capture and polishing chromatography steps for recombinant AAV (rAAV). The affinity capture step maximizes recovery and efficiently removes impurities.

Join this webinar to:
• Learn how to optimize affinity capture
• Discover critical parameters that enhance full and empty capsid separation
• See polishing data for several rAAV serotypes
• Explore common challenges and pitfalls – and ways to overcome them


To learn more or request a free sample of Capto™ Q, visit

Tags: AAV, downstream, capture, polishing, viral vector, gene therapy