November 19, 2020

A Small-Scale Model to Increase Yield in Cell Culture Perfusion of mAb at Large Scale

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As process intensification is adopted into large-scale manufacturing, the responsibility on scale-down models to accurately represent the expanded operating space quickly follows. Perfusion continues to be one such operating mode that lends itself to adding benefit at the manufacturing scale while adding complexity to the small-scale approach.

Tags: Bioprocess intensification, Intensified upstream, perfusion