April 19, 2024

Guide for selecting affinity resins for mAbs, bsAbs, and antibody fragments

Development of antibody-derived molecules are increasing. Today, molecules such as bispecific antibody (bsAb) and antibody fragments such as Fab, scFv, and VHH are seen in labs all over the world. These target molecules need to be purified to reach required purity and yield.

Selecting an affinity resin for the diverse range of antibodies can be overwhelming. But don’t worry, in this selection guide you will find the antibody affinity resin to achieve your required purity and yield. The selector chooses based on the structure of your monoclonal antibody, bispecific antibody, or antibody fragment and the impurity profile.

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Tags: chromatography, impurity profile, Affinity resin, VHH, scFv, Fab, antibody fragments, bsAb, bispecific antibody, antibody-derived molecules, antibody