May 3, 2024

Life cycle assessment of the protein A process in mAb manufacturing



We are reminded daily of how climate change is affecting our planet, and organizations all over the world have embraced sustainability and started to allocate attention and resources to sustainability development programs. Life cycle assessment (LCA), a systematic analysis of the environmental impact of a component or process from its material origin to its end-of-life deposition, is a common method for quantifying environmental sustainability.

Here we present a cradle-to-grave LCA for protein A chromatography resins in the capture step of mAb manufacturing. The focus is on the resin use phase, although resin manufacturing, packaging, distribution, and end of life will also be covered.

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Tags: Sustainability, Life cycle assessment, LCA, Protein A, chromatography