June 7, 2018

Optimization of Adenovirus Midstream Purification Steps

adenovirusAdenovirus (AdV)-based vectors are widely evaluated as vaccine delivery system in preclinical and clinical studies for various infectious diseases. In this application note, studies of midstream purification steps in an adenovirus production process is performed. Based on the results, suggestions for the choice of consumables and conditions for virus release and filtration is described.

To read the application note, click here.

Tags: virus release, cell lysis, midstream, adenovirus, viral vectors, vaccine manufacturing, vaccine