Bioprocess Development Forum - Insights, Solutions, and Shortcuts in Bioprocessing

April 8, 2021

Perfusion N-1 – A Way to Improve the Fed-Batch Production Process

Cytiva

In this article, we show how the conventional N-1 seed train step was replaced by a high-density perfusion and how the production bioreactor can be seeded at a 10-fold higher seed density compared with conventional runs.

Tags: N-1, perfusion, cell boost, actipro, Xcellerex XDR-500, XDR, Excllerex, bioreactor, process intensification, fed-batch, ReadyToProcess, seed train, cell culture