Rapid Process Development of a CIEX Step for a Bio


November 2, 2017 -

Sushma Nayak Teichert, Anna Maria Gudmundsdottir,

When establishing purification processes for a biosimilar molecule it is important to develop steps that are scalable, selective, and c

Repurposing Fed-Batch Media and Feeds for Highly P


October 19, 2017 -

Andreas Castan, Eric Fäldt, Audrey Vuillemez, Wil

The authors developed a method for identifying first-generation perfusion culture media based on existing fed-batch media and feeds. Here, t

A Next Generation Protein A Chromatography Resin f


October 5, 2017 -

David Westman, Annika Forss, Gustav Rodrigo, Thoma

mAb production using a Protein A capture step has followed a highly successful synergistic path the last 30 years. There are, however,

Impact of sporicidal agent on MabSelect SuReâ„¢ pr


June 28, 2017 - Cytiva

Bacterial endospore contamination constitutes a challenge in bioproduction due to their resistance to high concentrations of NaOH, comm

Strategies for optimized cell culture media: Effec


June 14, 2017 - EmmaLee Garner, Kalle Johnson, Mark Wight

Effective biopharmaceutical production is achieved in part through target-specific, quality-optimized cell culture media. Balancing the

Development of DoE based fed-batch strategies for


June 14, 2017 -

David Reinhart, Andreas Castan, Lukas Damjanovic,

Fed-batch culture is commonly employed to maximize cell and product concentrations in upstream mammalian cell culture processes. Typica

Adenovirus production in a single-use stirring tan


June 6, 2017 -

Teres Persson, Gustaf Ahlén, Susanne Stier, Mia B

Adenovirus vectors are attractive delivery systems for vaccines and cancer treatment. Scalable and cost-efficient production technologi

Case Study: Improve Process Economy by Cycling of


May 31, 2017 - Cytiva

The use of disposable technologies in downstream processing has increased significantly over the last years, as they reduce the need fo

Fast Trak Services: a collaborative project to acc


May 18, 2017 - Cytiva

Biosimilars represent an innovative solution that can benefit both patients and healthcare systems  by reducing the burden of rising tr

Resin selection to optimize the flexural strength


May 4, 2017 - Cytiva, Sealed Air Corp.

Single-use bioprocess technology offers several advantages for manufacturing biopharmaceuticals, such as increased transportability of

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