August 13, 2016

Columns up to 1600 mm in diameter packed with protein A chromatography medium using axial mechanical compression

Axial compression allows for optimally packed beds also in the large-scale chromatography column range. Different methods have been developed to pack a broad range of chromatography media (resins) in columns with axial mechanical compression. This includes packing of traditional BioProcess™ media, such as the Sepharose™ family, in addition to the more modern high-flow agarose media, like Capto™ and MabSelect™ family. For most media the packing parameters have been verified and implemented in a software application referred to as Intelligent packing and enable automated column packing. 

Learn more in this poster, presenting the efficiency of axial compression compared to traditional technologies and scalability.

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