Search results for " mechanistic modeling"
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Register to HTPD pre-conference day on mechanistic modeling
On Monday, October 30, 2023 in Malta, you will have the chance the join the Cytiva pre-conference sessions on mechanistic modeling, which will be followed by the 6th HTPD meeting.
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Using mechanistic modeling in process development for advanced therapeutics
Peter Guterstam and Nick Whitelock discuss mechanistic modeling in process developemnt of advanced therapeutics.
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Mechanistic chromatography models in a nutshell
Find out how mechanistic modeling simulates what happens in your chromatography columns.
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Cytiva and GoSilico Agree to Co-market ChromX™ Mechanistic Modeling Software
The agreement facilitates the adoption of ChromX™ by scientists and users of resins, columns, and chromatography systems into their downstream process-development workflows to accelerate development…
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Leveraging Computational Models of Glycosylation for Biopharma QA
This disparity may arise from the use of specialized software and the perceived need for expert user input associated with mechanistic modeling. Despite these challenges, mechanistic models are, conce…
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Discovering the unknown: How does in silico process development change PD scientists’ work?
One main benefit of mechanistic modeling to support chromatography process development is that a high level of process understanding is created with only a limited set of experiments. Once a mechanist…
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Using Digital Twins to Model Process Chromatography
The challenges of mechanistic modeling include the need to characterize the behavior of these systems, and the expertise required to use them effectively. Companies such as GoSilico (now part of Cytiv…
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Digitalization: The Route to Biopharma 4.0
Recently, a hybrid modeling approach, combining both mechanistic modeling and data-driven modeling, has been shown to offer a multitude of benefits. For chromatography, relating data from sensor with …
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Report from the 6th International HTPD Conference
A preconference day focused on getting up to speed with mechanistic modeling
This year, the week started with a pre-conference day about mechanistic chromatography modeling, organized by Cyt…
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Determining Criticality, Part Two: DoE and Data-Driven Criticality
A practical roadmap in three parts that applies scientific knowledge, risk analysis, experimental data, and process monitoring throughout the three phases of the process validation lifecycle.
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