Search results for " ÄKTA process"
Article
Mechanistic Modeling of Preparative Ion-Exchange Chromatography
By Anurag Rathore, Vijesh Kumar
Among the various downstream processing unit operations that are used for purification of biotech products, chromatography is uniquely capable of providing resolu…
Article
2019’s Top Bioprocessing Trends and What to Expect in 2020
2019 proved to be an exciting year for biopharmaceutical developers and process engineers, filled with both advancements and lessons. Considering how far the industry has come, what direction will 2…
Poster
Scale-up and process economy calculations of a dAb purification process using ready-to-use products
Purification of a domain antibody (dAb) in a chromatography capture step was successfully scaled from laboratory to pilot scale using ready-to-use equipment and ready-made buffers. The scaled-up pro…
Article
Industry Adoption of Single-Use Systems Remains Low
Single-use technologies are starting to gain ground as capacity needs change, but industrywide adoption remains low.
By Feliza Mirasol
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Article
Gain Efficiency in Process Development
The development of efficient manufacturing processes is a necessity for cost-effective production of biopharmaceuticals. By carefully designing and evaluating your experiments, sufficient informatio…
Article
Choose your Optimal Wavelength for Chromatography
ÄKTA™ chromatography systems and resins offer a wide range of solutions for isolating and purifying target molecules from research, through process development and manufacturing. With a variety…
Article
Connected Polishing and Concentration Under One Automation Method
Chromatography and tangential flow filtration (TFF) steps are traditionally performed as separate unit operations in downstream bioprocessing. This work aims to demonstrate the capability of the UNICO…
Article
Get a strong start in oligonucleotide manufacturing
Oligonucleotide therapeutics hold incredible promise. How can you harness their full potential? When starting process development, you need to know where to focus, and you need a scalable a…
Article
Efficient and Scalable Buffer Preparation
This article describes how to ensure a scalable process for buffer management from process development to manufacturing with inline conditioning (IC). It also explains how Ä…
Poster
Scaling In-Line Buffer Preparation from Process Development to Manufacturing
Preparing buffers for large-scale chromatography requires significant resources: time, money, and storage space. Inline conditioning (IC) is one possible way to address these challenges. At the same t…