Search results for " resins"
Article
Interpreting Protein Binding Capacities for Chromatography Resins
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Comparing the protein-binding capacities of resins from different suppliers is not straightforward because different methods may have been used and these methods are n…
Article
Sanitization of AxiChrom™ Columns Packed with Chromatography Resin
This study evaluates sanitization methods based on 1 M sodium hydroxide (NaOH) as sanitization agent using methodology previously developed for peracetic acid (PAA).
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Resource
A Route to Deeper Process Understanding—Studying Resin Variability Using a Process Characterization Kit
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Resource
Studying Resin Variability Using a Process Characterization Kit: A Route to Deeper Process Understanding
https://info.cytivalifesciences.com/QbD-webinar-register.html
Article
Process Chromatography: Continuous Optimization
Suppliers of chromatography resins are developing new resin chemistries and binding mechanisms to meet this need.
Several interaction modes
There are four major chromatographic techniques employed…
Article
A Look at the Affinity Chromatography Landscape
In addition to more base-tolerant resins, the selection of Protein A-based affinity resins has expanded to include resins with increased capacity and improved homogeneity of the chromatography beads, …
Article
Implementation of Raw Material Control Strategies in the Manufacture of Single-Use Bioprocessing Containers
Typical resins used in multilayer films include, but are not limited to, variants of polyethylene (PE) (e.g., low-density polyethylene [LDPE], linear low-density polyethylene [LLDPE], ultralow-density…
Article
Improving Process-Scale Chromatography
New resin chemistries
New chromatography resins and chromatography ligands are constantly being developed, according to Lotta Ljungqvist, head of bioprocess R&D for Cytiva. She points to several n…
Article
Making the Move to Continuous Chromatography
The manufacturer just needs the right equipment and expertise; the processes use the same buffers and resins as used in their current batch processes,” he says. “Ultimately, if you want to work faster…
Article
Development of Purification for Challenging Fc-Fusion Proteins
In this study, both CEX and HIC resins were evaluated in a flow-through mode as a polishing step in purification of Fc-fusion proteins that previously proved challenging to purify using conventional A…