Search results for " capacity"
Article
Downstream Processing Continues to Worry CMOs
…ng, according to BioPlan Associates 13th Annual Report and Survey of Biopharmaceutical Manufacturing Capacity and Production
(1). In fact, nearly two-thirds (64%) of CMOs surveyed for the study r…
Article
Enhancing Resins Addresses Purification Concerns
…o separate single-stranded RNA (ssRNA) from double-stranded RNA (dsRNA), and they have a low binding capacity (1,2). Deorkar notes that hydrophobic interaction chromatography (HIC) and anion exchange…
Article
A Plastic Pipeline for Commercial Bioprocessing?
The expansion will double manufacturing capacity at the site and will feature a mix of Thermo Fisher bioreactors, consumables, and factory automation. The expansion will be operational in 2019.
…
Article
Re-use of Protein A Resin: Fouling and Economics
It has been shown that the extended use of a resin results in decrease in its binding capacity, a decrease in product recovery, and a loss of Protein A ligands (9). Recent innovations in Protein A-aff…
Article
Comparing Protein A Resins for Monoclonal Antibody Purification
…), and vendors of mAb purification technologies must develop chromatography resins with high binding capacity to meet the demand. In addition, more cost-efficient cleaning procedures are necessary to…
Article
The Outlook for CMO Outsourcing in 2019
Routine services and products with smaller markets will be outsourced more frequently, and products requiring novel bioprocessing, where expertise or capacity remain limited, will also be outsourced m…
Article
Single-Use Technologies Prove Effective for Viral Vector Process Development
Need for higher commercial capacity
Many viral-vector manufacturing processes for gene therapies were initially developed in academic laboratories using traditional plasticware systems such as m…
Article
Genetic Vaccine Platforms Demonstrate Their Potential
Becker points out that currently there is only limited global capacity for biopharma production, some of which is required for existing drug and vaccine products. In addition, both traditional and gen…
Article
The Challenge of Disruptive Technologies in Bioprocessing
Thermo Fisher Scientific aims to address this challenge with a series of commercialized hydrophobic interaction chromatography resins with a differentiating range of hydrophobicity, resolution, high c…
Article
Contract Manufacturing Through the Years
The first was the shedding of excess capacity by global bio/pharmaceutical companies as older products went off patent and as the establishment of the European Union and North American Free Trade Agre…