Search results for " mixing" in Articles / App Notes
Article
What’s New in Upstream Technologies
The new SUB increases mixing efficiency within the bioreactor, resulting in an increased mass transfer coefficient (kLa) while maintaining the same rate of agitation.
“Optimized mammalian processe…
Article
A Plastic Pipeline for Commercial Bioprocessing?
A Plastic Pipeline for Commercial Bioprocessing?
The maturation of single-use technologies presents commercial bioprocessing options for small-volume drug products.
By Rita C. Peters
…
Article
Evaluating Surface Cleanliness Using a Risk-Based Approach
The mixing of the drain solution (heel) can reduce residue deposition on the side walls. Horizontal tanks, equipment surfaces, and piping should be sloped at 1/8–1/16 inches per square foot (3.6–1.8 c…
Article
Process Chromatography: Continuous Optimization
Improved resin chemistries and customized separation solutions are enabling more efficient separations.
By Cynthia A. Challener
Cell-culture and fermentation are high-…
Article
Managing Biomanufacturing Capacity Expectations
Capacity for complex therapeutics is becoming increasingly difficult to predict.
By Randi Hernandez
Demand for any given new product is typically only known after significant investments h…
Article
Continuous Processing for the Production of Biopharmaceuticals
The dynamic mixer at the beginning of the reactor configuration provides the rapid mixing that is required during addition of reduced protein to the refolding buffer, and the CFIR provides constant mi…
Article
Fluid Handling in Biopharma Facilities
Kaap (Parker domnick hunter): Besides open-vessel mixing, most single-use applications for bioprocessing steps involve low bioburden fluids being transferred. There is a trend to move to closed system…
Article
Video: Xcellerex XDUO 2500 Single-Use Mixer
It is a robust, versatile, and easy to use single-use mixer that can be used for mixing operations throughout the entire bioprocess workflow. Watch video.
Article
Taking a “Development-by-Design” Approach to Cell Therapies
Jun 15, 2015
By Agnes Shanley
BioPharm International eBooks
Volume 28, Issue 13
Whether outsourcing or developing cell therapies in-house, success demands a focus on quality, c…
Article
Concentrating Feed—an Applicable Approach to Improve Antibody Production
After mixing well, the solution was made up to the required volume and filtered through a 0.22 µm filter (Millipore). The pH and osmolality of the medium were measured. This medium is referenced as M2…