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Article Register now: Viral Vector Production for Gene Therapy
In partnership with NIBRT, our eLearning course, “Viral Vector Production for Gene Therapy”, is available on the award winning NIBRT Online Academy. READ MORE >>

Article Manufacturing of Vaccines and Viral Vectors
In this article, general guidelines for scaling up a viral vector and virus manufacturing processes are discussed.

Webcast Viral Vector Production for Gene Therapy (in partnership with NIBRT)
In partnership with NIBRT, our eLearning course, “Viral Vector Production for Gene Therapy”, is available on the award winning NIBRT Online Academy.

Article Lentiviral Vector Upstream Process in Single-use Bioreactors
Click here to read the article >>  Lentiviruses exhibit many desirable properties as gene transfer vehicles, such as high transduction efficiencies, ability to infect both dividing and nondivi…

Article Production of Recombinant Adeno-associated Virus Vectors Using Microcarrier Culture of HEK293T Cells
As of March 2020, more than 4310 gene therapy clinical trials have been performed worldwide, with only 518 of them in Phase III and Phase IV. As the gene therapy projects enter clinical Phase III or g…

Article Genetic Vaccine Platforms Demonstrate Their Potential
“This issue can make repeated dosing difficult, since with additional dosing, the patient’s immune system may clear the viral vector before it has an opportunity to insert the nucleic acid into a cell…

Article A Look at the Affinity Chromatography Landscape
…purification of not only novel protein-based biologics, but a wide range of other biomolecules, from viral vectors and nucleic acids to cells. Beyond impurity removal for “simple” proteins Af…

Article Emerging Therapies Test Existing Bioanalytical Methods
Another important assay for gene therapy programs is immunogenicity both to the viral vector and to the product of the transgene. Most of the vectors utilized are likely to have modifications that wil…

Article Maximum Output Starts with Optimized Upstream Processing
Viral vectors are a special case Viral vectors, which are used directly in therapeutics and vaccines and also in the production of gene and gene-modified cell therapies, represent a special case…

Article Design Considerations for a Commercial Cell and Gene Therapy Facility
“We have to split this discussion into two parts for a successful comparison: first, viral vectors for gene therapy and second, cell and ex-vivo gene therapy,” remarks Senthil Ramaswamy, head of R&D, …