Search results for " viral vector"
Article
Evaluation of HEK293 Cell Growth and Adenovirus Productivity in HyClone™ CDM4HEK293 Medium
HEK293 cells are susceptible to infection by adenovirus, one of the most frequently used viral vectors in the development of therapeutic vaccines and vaccines against infectious diseases. This applica…
Article
Milestones and Moderate Progress in 2012 Drug Approvals
Glybera is a replication-deficient adeno-associated viral vector housing a human lipoprotein lipase gene. The product is administered intramuscularly, and the resultant transduction of the surrounding…
Article
HTPD 2023 conference is coming up. What will be discussed and what happened last time?
Both the evolution of mature HTPD platforms for mAbs as well as the development of new HTPD approaches for nanoparticles like cells, viral vectors et al, will be discussed.
Learn more about HTPD …
Article
A better way to purify small drug volumes
But purifying viral vectors with methods optimized for other products can affect yield, purity, and cross-contamination.
How does the ÄKTA ready™ 450 system tackle those problems?
…
Article
Top Process Development Trends for 2021 and a Look into 2022
The COVID-19 pandemic continues to shape bioprocess development trends, and many lessons have been learned from industry’s response to and preparedness for dealing with a public health crisis. Howev…
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How to Optimize and Scale Up AAV Production
In this article from a roundtable discussion, four experts from academia and industry met to discuss challenges in refining and scaling up AAV production pipelines to meet the increasing demand for …
Article
Future Downstream Process Development Solutions for Advanced Therapies
Related Content
Q&As with Industry Leaders
mRNA manufacturing strategies
Manufacturing of viral vectors
Purification of plasmids
Oligonucleotide therapeutics
Article
HyClone Characterized FBS – Origin Equivalence Study
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Fetal bovine serum (FBS) is still used in many cell culture applications, including viral vector production. FBS from a single origin may be limited, so qualifying FBS from …
Article
Strategizing for Rapid Changeovers in Biologics Manufacturing
For certain biologics, most notably viral vectors, vaccines based on live viruses, and spore-formers, precautions must be taken to prevent spread through the air and more extensive cleaning protocols …
Article
Maximizing the Effectiveness of Upstream Bioprocessing Through the Combination of Lab Informatics and Instrumentation
By Claire Hill
The biopharmaceutical market continues to expand at a rapid pace and the demand for upstream manufacturing capacity, particularly for growth areas such as viral vectors, is growing …