Search results for " mRNA"
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Cytiva to provide Arranta Bio 'idea to injection' solutions for integrated manufacturing of mRNA products
Cytiva will provide its FlexFactory single-use manufacturing platform to Arranta Bio ("Arranta"), a leading contract development and manufacturing organization (CDMO) for use in manufacturing mRNAv…
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Genetic Vaccine Platforms Demonstrate Their Potential
Genetic vaccines use part of the virus’ own genetic code (either mRNA or DNA) to instruct cells to make a viral antigen that will stimulate an immune response. Viral-vectored vaccines allow selection …
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Can Vaccine Development Be Safely Accelerated?
Cambridge, MA-based Moderna—which has developed numerous prophylactic mRNA vaccines with positive Phase I clinical readouts and also has a fully integrated clinical-material manufacturing site—is prog…
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Top Process Development Trends for 2021 and a Look into 2022
They are further categorized into gene and cell therapies that use vectors such as AAVs, adenoviruses, and lentiviruses for delivery; oligo-based therapeutics such as anti-sense DNA, siRNA, mRNA, spli…
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Enhancing Resins Addresses Purification Concerns
The mRNA vaccines in particular are still rather new to the market, which is why no such platform processes seem to be in place.”
One common feature of all mRNA-based APIs is the poly(A) tai…
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Need solutions for large-scale production of mRNA-based molecules?
Compared with current therapeutics, mRNA production is more cost-effective, faster, and more flexible.
Interested in mRNA vaccines or therapeutics? Discover how we can support production and manuf…
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A Risk-Based Genetic Characterization Strategy for Recombinant CHO Cell Lines Used for Clinical and Commercial Applications
Evaluation of integrity of the transgene mRNA expressed in CHO cells
RNA splicing is a natural process in mammalian cells that removes introns and joins exons in a primary transcript to create matu…
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How can you harness the potential of nucleic acid therapeutics?
At Cytiva, the new team is here to support you. We can help you throughout the
development of your manufacturing workflow for oligonucleotides
and the purification of mRNA drug subs…
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A Closer Look at Affinity Ligands
… chromatography stationary phases to provide a highly specific ligand for the polyadenylated tail of mRNA [messenger RNA] molecules. The emergence of this class of therapeutic molecules (mRNAs) drove…
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Democratizing GMP Manufacturing for the New Therapeutic Pipeline
PharmTech Europe discusses technology that enables the “democratization” of mRNA manufacturing with Scott Ripley, general manager, Nucleic Acid Therapeutics and Precision Nanosystems, Cytiva, …