Search results for " chromatography system"

Article Making the Move to Continuous Chromatography
Continuous chromatography systems are designed to be loaded continuously, which is a useful approach when the purification step is connected to an upstream perfusion bioreactor. There are several diff…

Article Improving Process-Scale Chromatography
Equipment suppliers have also introduced or are developing continuous chromatography systems for use at the lab, pilot, and manufacturing scales. Both Cytiva and Pall have systems based on countercurr…

Article Process Chromatography Selection for Downstream Processing Applications
Similarly, if the pump capacity of the chromatography systems is insufficient, a smaller column or a change in the process flow rates may be required. Some of these challenges may be addressed through…

Article HT Multi-Product Liquid Chromatography for Characterization of Monoclonal Antibodies
If used correctly, these new analytical methods can reduce analysis and product development time. ABSTRACT Monoclonal antibodies represent a significant portion of sales in the biopharma…

Article Single-Use for Downstream Chromatography: Benefit or Hindrance?
Single-use in overall bioprocessing Suppliers of single-use downstream chromatography systems continue to improve the options available to manufacturers, and to examine ways to reduce the number of…

Article Reducing Cross-Contamination Risks in Process Chromatography
The main drivers for using single-use chromatography systems are batch size and frequencies, according to Morelli. “It becomes a balance between the total cost of operation and manufacturing agility, …

Article A Look at the Affinity Chromatography Landscape
A Look at the Affinity Chromatography Landscape New ligands are being developed to meet the separation and purification needs of next-gen biologics. By Cynthia A. Challener …

Article Evaluating the Use of Continuous Chromatography
…: Continuous chromatography differs from traditional ‘batch’ chromatography in two key ways: the chromatography system can be loaded continuously, which is a useful approach when the purification ste…

Article Technology Innovations Improve Process Chromatography Performance
As technology matures, inefficiencies and process limitations in downstream process chromatography are improved. By Feliza Mirasol Selecting an appropriate separation technology fo…

Article Optimizing Resin Performance with Disposable Chromatography Solutions
Interestingly, our customers normally purchase a single-use chromatography system before they start using a disposable column. The chromatography system is a long-term commitment to make, whereas a co…

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