Search results for " Biacore" in Articles / App Notes
Article
The Path to High-Quality Immunoassay Reagents
How Biacore surface plasmon resonance is shaping today’s assay development and selection of diagnostic reagents.
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Get Acquainted with How SPR Technology is Used for Better Protein Characterization
Surface plasmon resonance (SPR) has become a go-to tool for biotherapeutic characterization, and most approved antibody therapeutics have passed through a Biacore SPR system.
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Applications of Surface Plasmon Resonance for Detection of Bispecific Antibody Activity
The sample readout from an SPR system such as Biacore (Cytiva) is related to molecular mass and any binding event can be detected without the use of labels (Figure 2). The readout is continuous, which…
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Overview of a scale-up of a cell-based influenza virus production process using ReadyToProcess equipment
The virus content was determined by measuring the HA concentration by a Biacore method (7). The amount of infectious particles was analyzed by assaying 50% tissue culture infective dose (TCID50). The …
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Understanding Protein Production from Start to Finish
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In protein research, going from idea to pure characterized protein takes multiple steps and techniques. Most scientists working with exploring proteins and developing spe…
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Life Science Online Training: Build Your Skills and Continue Your Education
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Cytiva continuously adds courses to cover a spectrum of life science topics such as chromatography and bioprocessing. You can find valuable course content for researc…
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Tips for Purifying and Analyzing Cryo-EM Samples
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Cryogenic electron microscopy (cryo-EM) provides possibilities to determine structures for more challenging proteins, such as membrane proteins and larger protein compl…
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Purifying Samples for Cryo-EM Preps
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Technical improvements in cryogenic electron microscopy (cryo-EM) have triggered a revolution in structural biology and made single-particle cryo-EM …
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Epitope Binning: A Critical Step in Antibody Selection
Read about how surface plasmon resonance (SPR) is used to characterize closely related “bins” of monoclonal antibodies (mAbs) targeting the same epitope of the target protein, and how the selection …
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Getting it Right from the Start in the Drug Development Process
Proper process understanding allows researchers to critically identify factors that impact the drug substance and product as well as minimize or maintain them at approved levels. As a result, the de…