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Poster Fast Trak Services: a collaborative project to accelerate downstream biosimilar process development
To improve the availability, price and access of  medicines, many countries are implementing strategies to establish their own production capacity. To support this development, mAbxience, a Sp…

Poster Residual DNA analysis in influenza vaccine processing
To reliably measure residual DNA in both process samples and final vaccine by quantitative PCR (qPCR), DNA preparation prior to analysis is a necessity. Samples from the vaccine purification process c…

Poster A Next Generation Protein A Chromatography Resin for Improved Productivity and Bioburden Control
There are, however, remaining challenges. • The increased upstream titers in mAb production seen in recent years may make the Protein A capture step a bottleneck.  • Protein A columns columns …

Poster Rapid Process Development of a CIEX Step for a Biosimilar
A cation exchange (CIEX) chromatographic step was developed as part of a collaborative project, where expertise in the field of downstream purification and bioprocessing was combined with specific bio…

Poster Opportunities, Challenges, and Economic Drivers for Start-to-Finish Continuous Biomanufacturing
Many large biopharmaceutical organizations are exploring potential solutions to drive continuous operations on the manufacturing floor.  Continuous biomanufacturing carries the hope for achieving …

Poster Adenovirus production in a single-use stirring tank bioreactor system
Scalable and cost-efficient production technologies are needed to enable manufacturing of safe and efficacious clinical-grade virus. Anchorage-dependent cells cultured in roller bottles or cell factor…

Poster Scalable Continuous Chromatography Process for Enhanced Efficiency in Biomanufacturing
One such option explored is continuous, or connected, biomanufacturing. For continuous chromatography, interest in techniques such as periodic counter current chromatography (PCC) is increasing. …

Poster Strategies for optimized cell culture media: Effectively using design space to influence product quality
Balancing the many individual media components required to achieve high titers and support critical protein quality attributes can be challenging. Here we highlight a statistical design strategy to op…

Poster Scale-up and process economy calculations of a dAb purification process using ready-to-use products
The scaled-up process shows reproducible results over triplicate runs, indicating process robustness. Results from the scaled-up process were comparable with the process run at laboratory scale. In ad…

Poster Unlocking the potential for efficiency in downstream bioprocesses
Additionally, flexibility needs to be increased and time to market reduced. Upstream processes are more efficient and product higher titers than before. With these improvements, new challenges arise. …

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