Search results for " scalability" in Articles / App Notes
Article
Gene Therapies Push Viral Vector Production
Gene Therapies Push Viral Vector Production
Viral vectors show promise as a delivery mechanism for gene therapy, but which virus types are commercially viable?
By Feliza Miraso…
Article
Platform Approach Speeds Process Development
Depending on the development goals, different development modules can be selected to best fit the anticipated product quality profiles, safety, process robustness, and scalability. A custom set of mod…
Article
Exosome isolation by tangential flow filtration and size exclusion chromatography
- High productivity, scalability, and single-use compatibility were observed for the superSEC resin.
- Scaling up the SEC resin volumes using the superSEC resin was clearly shown with shorter pur…
Article
Genetic Vaccine Platforms Demonstrate Their Potential
In a pandemic, genetic vaccines offer several advantages over traditional approaches.
By Cynthia A. Challener
For a vaccine to be effective, the components of the disease o…
Article
Best Practices for Selecting a Top-Quality Cell Line
Defining high-quality cell lines
A high-quality cell line will demonstrate high stability, scalability, and high titer, so that it can provide reproducible results—with all product quality attribu…
Article
Techniques for Improving Process Development for Exosome-Derived Therapeutics
We have done this for the first project in our pipeline, scaled it up, and have seen good scalability of performance.
It is important to develop the initial process with a future platform in m…
Article
Single-use Bioreactors Have Reached the Big Time
In fact, an attractive attribute of single-use bioreactors is their full scalability, according to Adams. Today there are systems available for high throughput R&D through to commercial production. Sa…
Article
A deep dive into optimizing AAV capture and polishing to maximize both yield and purity
As demand for AAV vectors grows, so does the need for scalable and cost-efficient purification processes. It’s critical to maximize both overall yield and removal of impurities, including empt…
Article
mRNA: The Messenger - mRNA Product Purification
Join us for part 4 of mRNA : the messenger, where we discuss key considerations for the purification of the mRNA product, including the various methods available and how to consider scalability and su…
Article
Recombinant Adeno-Associated Virus Type 5 Production Process
A scalable recombinant adeno-associated virus (rAAV) type 5 production process was developed using transfected HEK293 suspension cells.
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