Search results for "adenovirus" in Articles / App Notes
Article
Achieve Scalable Viral Vector Production
In this episode, a scalable production process for adenovirus is presented.
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Webcast: Repeatable, automated SPR titer assay for adeno- and adeno-associated viruses in crude samples
Fredrik Sundberg at Cytiva shares our recent SPR assay developments for measuring adenovirus and adeno-associated virus titers.
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Commercial Production of Gene Therapies Using Suspension or Adherent Cell Lines
However, adenovirus and retrovirus are also of interest in this space (the latter being primarily used in Chimeric antigen receptor T (CAR-T) cell therapy and not as a primary vehicle). and must be pr…
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Genetic Vaccine Platforms Demonstrate Their Potential
“That is the beauty of genetic vaccines; they represent a platform approach with a central technology (adenovirus, liposome particle mRNA, or other) that can be readily modified by inserting a new gen…
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Manufacturing of Vaccines and Viral Vectors
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With the pandemic outbreak of COVID-19, there is intense focus on developing a vaccine. However, the challenge not only lies in developing a vaccine but also i…
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Flexible Facilities for Viral Vector Manufacturing
Single-use and modular systems will meet demand for rapid implementation at different scales.
By Jennifer Markarian
Industry experts have noted that there are limitations in the…
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Tips for Viral Vector Production
The viral vector market is highly active, and the interest in production technologies is driven by recent approvals in cell and gene therapy. In this blog article, insights are shared around the cha…
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Biopharmaceutical Process Development: 2018 Lessons and 2019 Predictions
…lication note describing the development of downstream chromatography steps for the purification of adenovirus from HEK293 cell culture harvest.
Single-Use Technologies Are Still Growing—But Not …
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Ensuring Viral Safety of Viral Vaccines and Vectors
In adeno-associated virus (AAV) processes, any replication-competent helper adenovirus must be inactivated and removed during downstream purification. AAV particles can resist heating at 52 ⁰C for 1…