Search results for "mRNA"
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Cytiva to provide Arranta Bio 'idea to injection' solutions for integrated manufacturing of mRNA products
Cytiva will provide its FlexFactory single-use manufacturing platform to Arranta Bio ("Arranta"), a leading contract development and manufacturing organization (CDMO) for use in manufacturing mRNAv…
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Genetic Vaccine Platforms Demonstrate Their Potential
Genetic vaccines include messenger RNA (mRNA)/DNA. Alternatively, vaccines can be classified into live and non-live vaccines, which is important when considering safety profiles.
Traditional v…
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Can Vaccine Development Be Safely Accelerated?
Prophylactic messenger RNA vaccines
Two companies, both also supported by grants from CEPI, have developed platform technologies based on messenger RNA (mRNA). Cambridge, MA-based Moderna—which ha…
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Top Process Development Trends for 2021 and a Look into 2022
However, the focus in 2021 shifted beyond the pandemic to optimization and scaling up adeno-associated virus (AAV) production, process workflows and considerations for messenger RNA (mRNA) therapeutic…
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Enhancing Resins Addresses Purification Concerns
What COVID-19 brings to the table
The COVID-19 vaccines comprise several possible and different modalities, such as messenger RNA (mRNA), attenuated viruses, viral vectors, proteins, and virus l…
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Need solutions for large-scale production of mRNA-based molecules?
mRNA therapeutics offer precise and individualized therapy and avoid manufacturing issues associated with recombinant proteins. Compared with current therapeutics, mRNA production is more cost-effecti…
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A Risk-Based Genetic Characterization Strategy for Recombinant CHO Cell Lines Used for Clinical and Commercial Applications
Evaluation of integrity of the transgene mRNA expressed in CHO cells
RNA splicing is a natural process in mammalian cells that removes introns and joins exons in a primary transcript to create matu…
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How can you harness the potential of nucleic acid therapeutics?
At Cytiva, the new team is here to support you. We can help you throughout the
development of your manufacturing workflow for oligonucleotides
and the purification of mRNA drug subs…
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A Closer Look at Affinity Ligands
…chromatography stationary phases to provide a highly specific ligand for the polyadenylated tail of mRNA [messenger RNA] molecules. The emergence of this class of therapeutic molecules (mRNAs) drove …
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Democratizing GMP Manufacturing for the New Therapeutic Pipeline
PharmTech Europe discusses technology that enables the “democratization” of mRNA manufacturing with Scott Ripley, general manager, Nucleic Acid Therapeutics and Precision Nanosystems, Cytiva, …