Search results for "bioproduction"
Article
Automating the Biomanufacturing Process
“Our ultimate goal is a ‘plugand-play’ system of automated bioproduction in which vendors, suppliers, and manufacturers all use equipment that ‘recognize’ each other, allowing for simple integration a…
Article
The Outlook for CMO Outsourcing in 2019
The historical picture of respondents to the annual BioPlan survey reporting that they do not outsource bioproduction is shown in Figure 1.
Figure 1: Biopharmaceutical manufacturing facilities …
Article
A Look at the Affinity Chromatography Landscape
…ody fragment technology, according to Laurens Sierkstra, affinity purification business lead in the BioProduction Division.
“We offer products targeting other domains on antibodies that suppor…
Article
QbD Improves Cell-Culture Process Control
Real-time quality control
Integrating process analytical technology (PAT) into the bioproduction process enables the biomanufacturer to move from a quality-by-testing approach to a QbD approach, w…
Article
The New World of Biopharmaceutical Manufacturing
…serum containers, and to highly engineered, complex devices that are now mainstream technologies in bioproduction. Over the past five years, these devices have steadily made progress in bioprocess op…
Poster
Impact of sporicidal agent on MabSelect SuRe™ protein A resin lifetime
Bacterial endospore contamination constitutes a challenge in bioproduction due to their resistance to high concentrations of NaOH, commonly used in sanitization procedures. Hence, there is an intere…
Article
From Darwin to Recombinant Fc Multimers
Topics from a Darwinistic viewpoint on how business models are evolving in the Life Science industry to breakthrough research data from Momenta Pharmaceuticals on a recombinant trivalent Fc protein …
Article
Automating Bioprocesses
Automation of stainless-steel systems and single-use systems differs in complexity.
By Jennifer Markarian
Both upstream and downstream biopharmaceutical processes have conventionally used st…
Article
Ensuring Sterility in Small-Scale Production
Susan Schniepp, distinguished fellow at Regulatory Compliance Associates, discusses how to ensure sterility when manufacturing small-scale parenteral batches.
By Susan J. Schniepp
Q. I am a …
Article
Managing Biomanufacturing Capacity Expectations
Capacity for complex therapeutics is becoming increasingly difficult to predict.
By Randi Hernandez
Demand for any given new product is typically only known after significant investments h…