Search results for " methods"
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Principles and methods for automated multistep protein purification
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Methods of Automated Multistep Protein Purification
Summarized questions related to methods of multistep processing.
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Tips for Purification Method Editing: Learnings from the Webinar
Useful tips and features were demonstrated, for example how to develop methods that are easy to maintain, reuse, and share.
The live Q&A session after the webinar provided many interesting questi…
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Tips for Protein Purification Method Editing
Find out how to quickly generate tailored automation methods in your UNICORN™ software in this blog.
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Development of column packing methods based on pressure flow measurements
…ompressed beds, and the optimization of a suitable degree of bed compression when developing packing methods for scale-up.
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Filtration methods to overcome new challenges in viral safety
41 and ICH Q5A, and outlines the detailed mechanisms governing effective virus filtration, demonstrating how both specific methods and advanced filter design can overcome these challenges.
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Perfusion Culture Using TFF or ATF as Cell Retention Method
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Perfusion processes have many advantages such as being favorable for product quality and supporting efficient facility utilization by offering the possibility…
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Connected Polishing and Concentration Under One Automation Method
Chromatography and tangential flow filtration (TFF) steps are traditionally performed as separate unit operations in downstream bioprocessing. This work aims to demonstrate the capability of the UNICO…
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Optimization of a two-step purification method for bispecific antibodies
Bispecific antibodies (bsAbs) have gained increasing interest over recent years because they can bind two antigens, offering unique modes of action compared to monoclonal antibodies. New and i…
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Optimization of a Two-Step Purification Method for Bispecific Antibodies
Alligator Bioscience AB develops antibody-based pharmaceuticals for cancer treatment, specializing in mono- and bispecific antibodies for tumor-directed immunotherapies. Alligator and Cytiva devel…
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Efficient Cleaning-In-Place Methods for Protein-Based Antibody Affinity Chromatography Resins
This whitepaper discusses cleaning of affinity resins intended for use in the purification of monoclonal antibodies and antibody fragments, for example, Fab fragments. Various cleaning strategies and …