Search results for "high-throughput"
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A Look at the Affinity Chromatography Landscape
He does note that the use of standard and multimodal resins and high-throughput screening technologies greatly aid in defining separation techniques.
Most importantly, Heldin adds that affinity…
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Scaling Up Novel Therapies
Some high-throughput tools are already used early on and in process characterization, allowing users to run many experiments in parallel at smaller scale, with less material and in less time. One exam…
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High Throughput Protein Purification at a Glance
Frida Henningson Johnson, Annelie Cajander, and Anne-Sophie Svensson share their knowledge about high-throughput protein purification with readers in this blog.
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Perfusion in the 21st Century
Perfusion support
One of the challenges faced by all companies that are exploring use of perfusion processes is the limited ability to use high-throughput methods in perfusion mode. Currently, the…
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Detecting Protein Aggregates and Evaluating their Immunogenicity
With MFI, researchers can now determine how particle groups vary in their samples, and with “new high-throughput screening software, users can instantly compare results across many samples,” notes Olc…
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Ligand-Binding Assays and the Determination of Biosimilarity
“High-throughput, kinetic assessment of target binding on cells for those targets that cannot be produced as soluble proteins remains a challenge for the industry,” she observes. Several companies are…
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Save the date for HTPD 2025
We are pleased to announce the 7th International Conference devoted to High-Throughput Process Development (HTPD) and smart PD, to be held May 26–29 2025 in Uppsala, Sweden.
The program and…
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How to Use Multiwell Plates With Manual Operation
High-throughput tools like PreDictor™ plates prefilled with chromatography resins make it possible to explore a large characterized space for optimizing process conditions. They save time and require …
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Webinar: Optimizing a HIC step with HTPD
This workflow includes the use of high-throughput process development (HTPD) plates to facilitate the choice of resin and initial conditions for column chromatography, and a design of experiments (DoE…
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Optimization of a HIC step for recombinant protein purification
Follow this step-by-step high-throughput process development (HTPD) workflow to determine the optimal resin and initial conditions for hydrophobic interaction chromatography (HIC).
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