Search results for " chromatography resin" in Articles / App Notes
Article
Single-Use for Downstream Chromatography: Benefit or Hindrance?
In traditional industrial mAb processes, large volumes of both chromatography resin and buffer are required, which translates into high operating expenses. Because chromatography resins make up a larg…
Article
Mechanistic Modeling of Preparative Ion-Exchange Chromatography
…x and detailed mechanistic model that is capable of describing mass transfer at the bead level for a chromatography resin and can be executed using a personal computer. Ion-exchange chromatography (I…
Article
Improvements in Protein A Chromatography
It was put on a chromatography resin in 1972 and commercialized in 1978. A patent was filed in 1973 and granted in 1986. The first significant protein A sales started in about 2000. It is likely that …
Article
Top Tips for Successful Development of Antibody Chromatography Processes
In this interview, Jakob Liderfelt, Product Manager at Cytiva, discusses main challenges faced during chromatography process development for mAbs and mAb variants such as fragments and bispecific a…
Article
Next Generation Process Chromatography
…es under positive pressure while carrying out the same purification that are currently achieved with chromatography resins at slower rates. Other convective flow adsorbers have existed in bioprocessi…
Article
Cytiva Advances Fiber Chromatography Technology with New Launch
The launch of HiScreen Fibro PrismA, the company’s newest product for early mAb purification process development strengthens Cytiva’s new fiber-based Protein A platform.
On Jan. 27, 2021, Cyti…
Article
Chromatography for the Diversified Antibody Pipeline
Furthermore, we have protein which interacts with the Kappa ligand and we have a new engineered version which has recently launched—the MabSelect VL is more alkali stable, which is expected from a chr…
Article
Capacity and Performance of a Next Generation Protein A Chromatography Resin
Click here to read application note: Capacity and performance of MabSelect™ PrismA protein A chromatography resin
For more information, visit MabSelect Protein A resins
Article
Exosome isolation by tangential flow filtration and size exclusion chromatography
We demonstrate a scalable workflow for the isolation of exosomes—a type of extracellular vesicle with significant potential for targeted drug/gene delivery. For research and development and di…
Article
As the therapeutic pipeline diversifies, chromatography toolboxes are expanding.
Development beyond traditional monoclonal antibodies (mAbs) is increasing, and today, we see antibody variants like multispecific and bispecific antibodies and antibody fragments. In mAb proc…