Search results for " sec"
Article
Handbook: Size Exclusion Chromatography Principles and Methods
The first step towards a successful separation is to select the correct medium and this handbook focuses on the most up-to-date SEC media and prepacked columns.
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Article
Elucidating Biosimilars Characterization
…ight into the impact of alterations in the primary sequence or post-translation modifications on the secondary, tertiary, or quaternary structure of the protein. Traditional techniques such as X-ray …
Article
Virus and exosome purification: harness core bead technology
Using core bead technology to fine tune impurity removal and maximize recovery of
large entities.
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Article
Enhancing Resins Addresses Purification Concerns
Christoph Burgstedt/Stock.Adobe.com
Enhancement of resin technology can improve the ability of chromatography to purify the growing landscape of increasingly complex biomolecu…
Article
Preclinical Evaluation of Product Related Impurities and Variants
Preclinical Evaluation of Product Related Impurities and Variants
The approaches for sample preparation of preclinical evaluation of safety and efficacy are addressed taking into consideration the s…
Article
ADC Development Robust Despite Lackluster Performance
This ADC is expected to go into a Phase II trial in metastatic urothelial cancer in the second half of 2017 and has been undergoing a Phase I trial evaluating its safety and antitumor activity in esca…
Article
How to Optimize Protein Desalting
Most protein purification workflows require desalting, buffer exchange, or both at one or more steps. But how do you determine which method to use? And how do you choose the right product for your n…
Article
Capto™ Core 700 in Vaccine Processing
The aim with this white paper is to discuss the advantages of using Capto Core 700 in virus purification compared to size exclusion chromatography (SEC), a technique commonly used in several vaccine…
Article
Host-Cell Protein Measurement and Control
Jun 01, 2015
By Fengqiang Wang, PhD, Daisy Richardson, Mohammed Shameem
BioPharm International
Volume 28, Issue 6, pg 32–38
Host-cell proteins (HCPs) constitute a major part of proce…