Search results for " productivity"
Article
Recombinant Adeno-Associated Virus Type 5 Production Process
A scalable recombinant adeno-associated virus (rAAV) type 5 production process was developed using transfected HEK293 suspension cells.
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Webcast
The GMP of AAV: Purification for Clinical Production
What should you consider when developing a purification process for adeno-associated viruses (AAV)? We’ll share some insights on that topic. And we’ll discuss ways to overcome the key challenges in …
Article
Tips for Viral Vector Production
The viral vector market is highly active, and the interest in production technologies is driven by recent approvals in cell and gene therapy. In this blog article, insights are shared around the cha…
Poster
A Scalable Adenovirus Production Process, from Cell Culture to Purified Bulk
Adenovirus (AdV) vectors are commonly used in cancer gene therapy trials and evaluated for use in vaccines for various diseases. In this study, we have combined technical evaluation of process steps a…
Resource
Plasma Product Biotechnology Conference
The Plasma Product Biotechnology Conference Series, now in its 12th year, will provide a topical and stimulating program detailing the latest developments of importance to the industry. The sessions…
Article
Process Economic Simulation for Scalable Production of Adenovirus
This application note discloses the process economic modelling of a modern start-to-finish adenovirus production process. The novel process was compared with a reference process in both stainless-st…
Article
Achieving Efficient Adenovirus Upstream Production
Adenovirus is one of the most frequently used viral vectors in the development of therapeutic vaccines and vaccines against infectious diseases. Adenovirus has also been explored as a viral vector f…
Poster
Repurposing Fed-Batch Media and Feeds for Highly Productive CHO Cell Perfusion Processes
The authors developed a method for identifying first-generation perfusion culture media based on existing fed-batch media and feeds. Here, they show that they can obtain culture media that successfull…
Article
Evaluation of HEK293 Cell Growth and Adenovirus Productivity in HyClone™ CDM4HEK293 Medium
Adenovirus productivity was evaluated in shake flask cultures. Performance in CDM4HEK293 was compared with performance in a reference medium.
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Poster
Strategies for optimized cell culture media: Effectively using design space to influence product quality
Effective biopharmaceutical production is achieved in part through target-specific, quality-optimized cell culture media. Balancing the many individual media components required to achieve high tite…