Search results for " in silico"
Article
Digitalization: The Route to Biopharma 4.0
The equipment can be interfaced with the corresponding digital twins using sensors and actuators such that the real time data is fed to the digital twins and the in silico predicted can be employed fo…
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Digitalized PD: Speeding up downstream process development
Mechanistic models enable the simulation of chromatography processes based on fundamental natural laws, such as fluid dynamics and thermodynamics. In silico simulations of chromatography proce…
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Mechanistic modeling quiz: Test your knowledge
The benefit of in silico process development based on a mechanistic model? You can test thousands of purification options in a few hours.
How well do you know mechanistic chromatography modeling? …
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Sign-up to join Chromatography Virtual Summit 2022
High-level agenda:
• 15 November: Process development of antibody variants
• 16 November: In silico downstream process development — Get started
• 17 November: In silico downstream …
Article
Using Quality by Design to Develop Robust Chromatographic Methods
In the example, the data from the six experiments are used as the input for in silico optimization experiments. The result is a resolution map and optimized chromatogram within which the optimum condi…
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Predicting Progress in Protein Aggregation
“We have been successful to date in using such in silico analyses to address the issue of protein aggregation much earlier in the drug development process, which helps avoid potential problems through…
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Program finalized for the 6th HTPD and smart PD conference
Talks will cover everything from in silico PD and mechanistic modeling, HTPD approaches to chromatography resin screening and optimization, process characterization of gene therapy viral vectors to es…
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Better bioprocess scaleup with Bioreactor Scaler Pro
Are you still using the manual input, trial-and-error method when scaling your cell culture process, spending long hours in the lab analyzing uncertain data?
With Bioreactor Scaler Pr…
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See a chromatography modeling software in action
Mechanistic models use computer simulations to decrease the number of experiments you need during process development.
The simulations are based on known physiochemical phenomena involved in ch…
Article
Accelerating VLP purification process development
Further, they allow for efficient process optimization in silico.
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