Search results for " disposables"
Article
Industry Adoption of Single-Use Systems Remains Low
Monge, “Quantitative Economic Evaluation of Single Use Disposables in Bioprocessing [5],” Pharmaceutical Engineering. 22: 20-34 (2002).
5. Cytiva, “Cytiva Enhances Single-Use Manufacturing C…
Article
Automating Bioprocesses
Automation of stainless-steel systems and single-use systems differs in complexity.
By Jennifer Markarian
Both upstream and downstream biopharmaceutical processes have conventionally used st…
Article
Continuous Chromatography: Trends, Definitions and Approaches
The ultimate goal might be to combine disposables and continuous chromatography. Do you foresee any specific challenges?
This is an interesting question. Once I heard a comment that disposable tec…
Article
Technologies and Practices Must Evolve to Meet Demand
Jan 01, 2015 By Rita Peters
Through Dec. 3, 2014, nearly 30% of FDA’s new drug approvals for 2014 were for biologic-based therapies, up from 7% in 2013 (1). As the percentage of large-molecule …
Article
Securing the Single-Use Supply Chain
Dual sourcing is one of many possible solutions to securing the supply chain.
Single-use systems (SUS) have become established in biopharmaceutical drug development. As confidence in the technol…
Article
Trends in Single-use Bioreactors
Representatives from industry supplier companies address innovations, reliability, barriers to adoption, and the role of singIe-use bioreactors in bioprocessing.
By: Randi Hernandez
Whil…
Article
Overview of a scale-up of a cell-based influenza virus production process using ReadyToProcess equipment
Furthermore, disposables minimize the risk for cross-contamination between production batches, and the need for time-consuming and costly cleaning and validation procedures is made redundant.
Si…
Article
Single-Use Technologies Prove Effective for Viral Vector Process Development
The benefits of single-use technologies for upstream viral-vector processes clearly outweigh their disadvantages.
Cynthia A. Challener
Upstream viral-vector processes can have sig…
Article
The New World of Biopharmaceutical Manufacturing
Over the past eight years, the reasons biomanufacturers give for not expanding their use of disposables have been relatively consistent. Top concerns are the potential for breakage of bags/loss of pro…
Article
Downstream Processing for Cell-Based Therapies
The capital investment needed, together with the cost of disposables, demands careful consideration when carrying out process development (6).
Tangential flow filtration (TFF) offers an alternativ…