Search results for " single-use bioreactor"
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Lentiviral Vector Upstream Process in Single-use Bioreactors
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Lentiviruses exhibit many desirable properties as gene transfer vehicles, such as high transduction efficiencies, ability to infect both dividing and nondivi…
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Scaling a mAb production process to Xcellerex bioreactors
Moving a monoclonal antibody production process from a microscale bioreactor to the Xcellerex XDR single-use platform.
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Single-Use Technologies Prove Effective for Viral Vector Process Development
Large-scale single-use bioreactors, when compared to flatware systems, also require much less plastic to produce the same quantity of viral vector product, according to Cameau. That means the quantity…
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A Plastic Pipeline for Commercial Bioprocessing?
These advancements will theoretically allow for broader adoption of single-use bioreactors.”
Loeillot noted that a majority of the products in Cytiva customers’ monoclonal antibody pipelines re…
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The New World of Biopharmaceutical Manufacturing
Pora (Pall): We have come a long way from the first stirred tank bioreactor—even the way single-use bioreactors look has changed—with a broad range of solutions from small to large scale. As single-us…
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Reducing Cross-Contamination Risks in Process Chromatography
Today, single-use bioreactors are widely used for biologic drug manufacturing, and downstream disposable technologies for commercial-scale production operations are being introduced and increasingly a…
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Industry Adoption of Single-Use Systems Remains Low
“It is far more common today that biopharma manufacturers are building small economical facilities with several 2000-L single-use bioreactors--20 years ago, the companies were building a facility with…
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Securing the Single-Use Supply Chain
“Genentech recently presented a proof-of-concept design for a single-use bioreactor that could work with top- and bottom-mounted bags from two different suppliers. The next step is convincing manageme…
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Single-Use for Downstream Chromatography: Benefit or Hindrance?
Single-use technology is gaining ground in downstream bioprocessing, but challenges stall further adoption.
By Feliza Mirasol
ARTMOIS/STOCK.ADOBE.COM
Biopharmaceutical manufactu…
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Advancing Single-Use Technology Through Collaboration
By working together to harmonize the highly variable steps within the biopharmaceutical manufacturing process, both end users and suppliers are making strides toward the efficiency and integrity of …