Search results for " mixed mode"
Article
Determining Criticality, Part Two: DoE and Data-Driven Criticality
A practical roadmap in three parts that applies scientific knowledge, risk analysis, experimental data, and process monitoring throughout the three phases of the process validation lifecycle.
T…
Article
Discovering the unknown: How does in silico process development change PD scientists’ work?
This resulted in improvements in purity and yield of a mixed mode chromatography purification step, and doubled productivity. Mechanistic modeling can also support early-phase development. The technol…
Article
Chromatography for the Diversified Antibody Pipeline
You may need mixed mode interactions where both iron exchange and pure hydrophobic interactions occur. We have multimodal resin which is good at aggregate removal which targets product related impurit…
Article
Adsorption isotherm models for chromatography
In this article we will discuss adsorption models for ion exchange, hydrophobic interaction, and mixed mode chromatography.
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Article
Improving mAb Manufacturing Productivity by Optimizing Buffer and Media Prep Process Flow
Innovative approaches, including ready-to-use materials and in-line dilution, can significantly streamline overall bioprocessing operations.
By: Pranav Vengsarkar and Nandu Deorkar
I…
Article
The New World of Biopharmaceutical Manufacturing
Industry experts discuss the single-use revolution and changes to upstream and downstream processing equipment.
By Jennifer Markarian
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Article
Evaluating E&L Studies for Single-Use Systems
Extraction studies demonstrate approaches for evaluating single-use bio-pharmaceutical manufacturing materials.
By Irene Cecchini, Daniele Mastroianni, Silvia Rocchi, Gabriella Angiuoni
Biop…
Article
Modular Manufacturing Platforms for Biologics
May 01, 2015
By Randi Hernandez
BioPharm International
Volume 28, Issue 5
It should come as no surprise that the good design principles governing the execution of pharmaceutical manu…
Article
Trends in Single-use Bioreactors
Representatives from industry supplier companies address innovations, reliability, barriers to adoption, and the role of singIe-use bioreactors in bioprocessing.
By: Randi Hernandez
Whil…